15 results
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #Diagnosis
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... (Acute: previously ... structural kidney injury ... - No other cause ... - No other cause
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
- Differential Diagnosis ... Causes include: ... level <100 pg/ml EKG ... #differential #diagnosis ... #cardiology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... for alternative causes ... dechallenge • Acute ... #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Prednisone 5mg/kg ... Imaging: CXR- pulmonary ... #management #hematology ... #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... unless worrisome EKG ... Syndrome #TLS #diagnosis
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... quantify renal injury ... recent DAN) • EMG ... Goodpasture's cause ... #management #treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
liver or renal injury ... before beginning treatment ... cardiac output - Acute ... pulmonary edema ... peritonitis - Acute
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
cytotoxic lung injury ... starting amiodarone treatment ... pleural effusions • Acute ... acute respiratory ... Exclude other causes
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Culture (+): Acute ... Cerebral > Splenic, pulmonary ... Injury By: • Early ... ↑ ESR, CRP • EKG ... #management #cardiology