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liver syndrome algorithm hematology hepatorenal hrs blood chemistry chronic cirrhosis differential dili druginduced failure gastroenterology hepatitis hrsaki hrsckd hrsnaki interpretation
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Kidney Failure Coagulation ... Failure Infections Alcohol-Associated ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology ... #diagnosis
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... (Acute: previously ... structural kidney injury ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... dechallenge • Acute ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure (ALF ... • Albumin • Coagulation ... ALT Ratios: • Alcoholic ... liver #chemistry #diagnosis ... #differential #Hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... unless worrisome EKG ... #management #hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
cirrhosis, severe alcoholic ... hepatitis, or acute ... • Caused by splanchnic ... ., alcohol, virus ... Hepatorenal #Syndrome #Hepatology
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... exclude other causes ... kidney injury with ... goal of >21 kcal/kg ... #Algorithm #hepatology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... - Acute Hemolytic ... Lung Injury (TRALI ... #Transfusions #diagnosis ... #management #hematology
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