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hematology differential syndrome hepatorenal hrs liver product reactions treatment alcoholic algorithm cardiology chemistry chronic cirrhosis dic disseminated endocarditis failure gastroenterology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Kidney Failure Coagulation ... Drug-Induced Liver Injury ... Failure #Cirrhosis #Hepatology ... #diagnosis
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Acute Kidney Injury ... Glomerular (red blood ... eosinophils/white blood ... #Kidney #Injury ... #AKI #Differential
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Syndrome (HRS) - Diagnostic ... Criteria HRS-AKI ... (Acute: previously ... structural kidney injury ... HRSAKI #HRSNAKI #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... ABO incompatible blood ... #diagnosis #causes ... #treatment #management ... #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Failure (ALF ... • Albumin • Coagulation ... intestines, White blood ... liver #chemistry #diagnosis ... #differential #Hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... fever - ACS, AKI ... , acute limb ischemia ... unless worrisome EKG ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... - Acute Hemolytic ... Lung Injury (TRALI ... #Transfusions #diagnosis ... #management #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... quantify renal injury ... recent DAN) • EMG ... reveals increasing blood ... #management #treatment
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Microbiology: Blood ... Culture (+): Acute ... Injury By: • Early ... ↑ ESR, CRP • EKG ... #management #cardiology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Transfusion Related Acute ... Lung Injury (TRALI ... #Transfusion #diagnosis ... #management #hematology
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