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diagnosis hematology treatment algorithm anemia blood differential product reactions aplastic bruising cabcde classification coagulation crisis dic disorders disseminated essential et
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... Rare • Drugs (e.g ... Coagulation #Bleeding ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Chronic Disease Normal ... 80-100 fL) • Bleeding ... Chronic Disease (e.g ... #Hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... in mild cases) ... hemophilia type (e.g ... Chronic Management ... #treatment #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Treat primary cause ... - APTT < 1.5 x normal ... Coagulation #diagnosis #causes ... #treatment #management ... #hematology
Pediatric Trauma Primary Survey: C-ABCDE C - Catastrophic Bleeding - Life-threatening hemorrhage • Apply direct pressure/compression bandage
Pediatric Trauma ... assess for neck injury ... shock - ↓HR, ↓BP, Abnormal ... #Pediatrics ... Survey #CABCDE #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... ecchymoses, mucosal bleeding ... and petechiae Causes ... Anemia #oncology #hematology ... #diagnosis #management
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Drug history, e.g ... non-accidental injury ... connective tissue, e.g ... History #peds #pediatrics ... #diagnosis #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Causes purpura & ... Related Acute Lung Injury ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... Related Acute Lung Injury ... coagulopathy & ↑bleeding ... Transfusion #diagnosis #management ... #hematology #reactions
Pheochromocytoma - Diagnosis and Management Summary 10 percent rule = 10% of pheochromocytomas are extra-adrenal, multiple, bilateral,
bilateral, malignant, pediatric ... cases, not associated ... hypertension; some normal ... diagnostic procedures (eg ... adrenoceptors, potentially leading
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