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diagnosis sle erythematosus neurology pulmonary systemic toxicity amiodarone bells blood cerebritis classification cns cryoglobulinemia cryoglobulins dermatology differential hcq hematology hydroxychloroquine
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Summary • Epidemiology ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
• Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management ... #treatment
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Muscle Toxicity - Summary ... GBS), systemic lupus ... Direct muscle injury ... (SAMS-CI) • EMG ... myopathy #diagnosis #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... causing endothelial injury ... • They can cause ... . systemic lupus ... classification #rheumatology
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Summary - GrepMed ... CNS inflammatory cause ... ) • EMG/NCS (rare ... prevent corneal injury ... #Treatment #Neurology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager Summary ... quantify renal injury ... Goodpasture's cause ... differential #diagnosis #management ... #treatment
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Lung Toxicity Summary ... cytotoxic lung injury ... starting amiodarone treatment ... Exclude other causes ... Pulmonary #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Transfusions One Pager Summary ... in recipient (e.g ... Related Acute Lung Injury ... Transfusions #diagnosis #management ... #hematology #reactions
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