21 results
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Generally affects long ... • Differentiate ... #Disease #differential ... #diagnosis #causes ... #hematology
Rare Causes of Abdominal Pain
 • Hereditary Angioneurotic Edema - Recurrent visceral that may by swelling
painAbdominal ... Positive Carnett's sign ... accompanied by joint ... #Pain #differential ... #diagnosis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
effusion, Restrictive lung ... valve lesions Abdominal ... pain (20%) Renal ... erythematosus #signs ... #symptoms #diagnosis
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
Symptoms: cough, abdominal ... distension, wheeze, abdominal ... : weight gain, lung ... HFrEF may lack lung ... of CXR congestion
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... • Interstitial lung ... System Tender points ... #pain #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... #pain #Differential ... #Diagnosis #MSK ... #rheumatology #
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
nausea, vomiting, abdominal ... pain, headache, ... AP, ↑INR, ↑BUN/Cr ... infiltration) Differential ... Diagnosis: Viral
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
in HIV - Differential ... Diagnosis Framework ... • CT: Halo sign ... lymphadenopathy, • Abdominal ... AIDS #pulmonary #differential
Portal Venous Gas on Point of Care Ultrasound (POCUS) secondary to Necrotizing Pancreatitis

Adult male with abdominal
Venous Gas on Point ... pain/hypotension ... Diagnosis/Differential ... Age dependent differential ... Also seen s/p CPR
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, fever, joint pain ... , weight loss, abdominal ... manifestations, hypoxia, CXR ... #Leukemia #Hematology ... #Oncology #Diagnosis