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signs arthritis systemic joint pain treatment erythematosus lupus msk oncology rheumatoid sle syndrome classification disease disorders hemophagocytic hlh lymphohistiocytosis scleroderma
Systemic Sclerosis (Scleroderma) Limited - CREST: • Calcinosis • Raynaud phenomenon • Esophageal dysmotility • Sclerodactyly •
Internal Organs: • Joint ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Approach to a Positive (+) Rheumatoid Factor (RF) (+) RF does not always = RA Rheumatic disorders: •
disorders of Liver & Lung ... Malignancies • Aging ... Rheumatoid #Factor #RF #rheumatology ... #laboratory #differential ... #diagnosis
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
knees, shoulders Signs ... & Symptoms: • ... • Ultrasound Diagnosis ... : CLINICAL DIAGNOSIS ... #management #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and Symptoms: ... (interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Generally affects long ... • Differentiate ... SickleCell #Disease #differential ... #diagnosis #causes ... #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Myositis 4% - Lung ... autoantibodies #signs ... #symptoms #mimickers ... #differential # ... rheumatology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Symptomatic anemia Diagnosis ... #management #treatment ... #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
workup for specific symptoms ... organ-specific signs ... or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Approach to Joint ... or nerve root Symptoms ... #Pain #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis
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