122 results
Cutaneous and Systemic Findings in Dermatomyositis
Cutaneous Findings:
 - Heliotrope sign and edema
 - Nail-fold changes
 -
- Interstitial lung ... disease - Gastrointestinal ... tract - Cardiac disease ... Dermatomyositis #Diagnosis ... #Rheumatology
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
Anterior Knee Pain ... with possible symptoms ... kneeling worsens pain ... pathophysiology #diagnosis ... #signs #symptoms
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
and Symptoms: ... (interstitial lung ... disease), PAH ( ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Internal Organs: • Joint ... #Scleroderma #diagnosis ... #signs #symptoms ... #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
or nerve root Symptoms ... of Joint Disease ... disease must be ... #Pain #MSK #rheumatology ... #differential #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Cell Disease Vaso-occlusive ... Generally affects long ... #Disease #differential ... #diagnosis #causes ... #hematology
Manifestations of IgG4-related disease by organ system.
 The most common primary disease features are indicated in
of IgG4-related disease ... common primary disease ... Organs #Systems #Diagnosis ... #Hematology #Signs ... #Symptoms
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... #pain #skin #rashes ... #differential #diagnosis ... #rheumatology
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
Stimulation of joint ... subchondral bone -> Pain ... nociceptors -> Pain ... pathophysiology #diagnosis ... #signs #symptoms
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
or metastatic disease ... ketoconazole, etomidate) Symptoms ... anorexia, abdominal pain ... pain (10-40%), ... Insufficiency: Long-term