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signs differential management msk pathophysiology arthritis joint systemic erythematosus hematology lupus pulmonary ra sle adrenal ankylosingspondylitis cardiology endocrinology extraarticular infections
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... of Joint Disease ... disease must be ... #Pain #MSK #rheumatology ... #differential #diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
and Symptoms: ... (interstitial lung ... disease), PAH ( ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Cell Disease Vaso-occlusive ... Generally affects long ... #Disease #differential ... #diagnosis #causes ... #hematology
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
or metastatic disease ... ketoconazole, etomidate) Symptoms ... Insufficiency: Long-term ... , infiltrative diseases ... , check point inhibitors
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Scotoma, Ocular pain ... /pain upon eye movement ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
lesions Abdominal pain ... (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... • Interstitial lung ... • Shrinking lung ... System Tender points ... #diagnosis #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
knees, shoulders Signs ... & Symptoms: • ... pain / swelling ... : CLINICAL DIAGNOSIS ... #management #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... noninflammatory Signs ... constitutional symptoms ... #Diagnosis #MSK ... #rheumatology #
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
diseases features ... pain, swelling, ... pain), especially ... Extra-articular signs ... #symptoms #diagnosis
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