25 results
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... • Most common cause ... Abscess Pathophysiology ... Lung Abscess - Clinical ... : • CBC - Leukocytosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... Generally affects long ... #differential #diagnosis ... #causes #hematology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
auricular papules Clinical ... severity of the disease ... anti-NXP2 Abs Lung ... #rheumatology #dermatology ... #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... • Severe Liver Disease ... #Coagulation #diagnosis ... #causes #treatment
Bullous Pemphigoid - Diagnosis and Management Summary
Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Management Summary Pathophysiology ... epidermis from dermis Clinical ... - Erosions and crusts ... not feasible CMC ... #Management #dermatology
Based on the images alone, it is usually not possible to determine the cause of the
determine the cause ... level and high D-dimer ... nodular interstitial lung ... disease, that is ... #Clinical #Diagnosis
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Advanced HIV (CD4 ... : Clinical Manifestations ... Lung Disease: ... • Clinical (Symptoms
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
late adulthood • Diagnosis ... to 8 years Clinical ... • Chronic lung ... lymphocytic interstitial lung ... DDX - Other causes
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Assessment • Clinical ... Drugs, Unknown cause
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases ... Clinical Signs ... decreased reflexes Pathophysiology ... intervention CMC