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management hematology treatment hemophagocytic hlh infections infectiousdiseases lymphohistiocytosis summary syndrome abscess adjusted age anemia antimda5 antimda5dm aortoenteric arteritis arthritis autoimmune
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
age, which can cause ... @DharSaty #Ddimer ... #dimer #pathophysiology ... #hematology #differential ... #diagnosis #age
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... • Differentiate ... #diagnosis #causes ... #hematology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... Abscess Pathophysiology ... Lung Abscess - Clinical ... : • CBC - Leukocytosis ... Abscess Differential
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
auricular papules Clinical ... anti-NXP2 Abs Lung ... Men • ~50% of cases ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... organ damage Clinical ... Treat primary cause ... #Coagulation #diagnosis ... #causes #treatment
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Case description ... prior signs or clinical ... surgeon had a clinical ... Differential diagnosis ... #msk #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... accumulation of clinical ... Drugs, Unknown cause ... treatment #summary #rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Advanced HIV (CD4 ... Pulmonary Disease: Clinical ... • Clinical (Symptoms ... NTM #Infections #differential
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... likelihood of negative clinical ... #Bandemia #differential ... #WBC #CBC #hematology ... #pathophysiology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Non-autoimmune rheumatologic ... #Rheumatology
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