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differential symptoms systemic dermatology lupus sle causes dermatomyositis joint pain antimda5 antimda5dm antinxp2 antinxp2dm arthritis autoantibodies autoimmune bone disease jointpain
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Vesicopustule on erythematous ... • Cholesterol emboli ... Discoid lupus erythematosus ... #differential #diagnosis ... #rheumatology
Vascular Joint Pain - Differential Diagnosis Algorithm - Constant Pain (Ischemia) - Acute Onset -
Vascular Joint Pain ... - Differential Diagnosis ... Algorithm - ... e.g. fractured long ... #Algorithm #Orthopedics
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... Systemic #Lupus #Erythematosus ... #signs #symptoms ... #differential #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... Arthritis: • Joint ... and leukemia • Lung ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... Generally affects long ... predispose to other orthopedic ... #differential #diagnosis ... #causes #hematology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
skin thickening Signs ... (interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... violaceous macules and erythematous ... anti-NXP2 Abs Lung ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... Pulmonary: Parenchymal lung ... Musculoskeletal: Joint ... #Symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... ischemia • Skin: Erythematous ... Palpable purpura, joint ... #Rheumatology
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