13 results
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Increased red cell ... Reticulocytosis/polychromasia ... hyperplasia of bone ... Increased red cell ... #Algorithm #Differential
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
= Hypocellular bone ... • Suggested by bone ... hypoplasia/fatty bone ... anemia Treatment ... #Anemia #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... with hypocellular bone ... Treatment: • Consider ... stem cell transplant ... #management #treatment
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... ) • Enostosis/bone ... docskalski #Knee #Bone ... Tumors #Diagnosis #Bony ... #Differential #
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... = funny-shaped cells ... cytopenias (usually anemia ... • Bone marrow ... #hematology #oncology
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Primary Bone Tumors ... Non-Malignant • Giant Cell ... • Aneurysmal Bone ... Histiocytoma #Primary #Bone ... #Bony #Tumors #
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
different types of bone ... Simple/unicameral bone ... • Aneurysmal bone ... Healed NOF • Giant cell ... #Differential #
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... megakaryocytic Bone ... • Aplastic Anemia ... • Bone Marrow ... in the bone marrow
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Hypoproliferative (i.e. bone ... Hypogonadism • Bone ... marrow failure: Aplastic ... Hyperproliferative (i.e. bone ... #differential #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment ... Warm AIHA • Bone ... diagnosis #workup #oncology