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diagnosis hematology management causes radiology algorithm bony msk tumors workup chronic classification knee lesions lymphocytic mds myelodysplastic xray acidosis adult
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... Phosphorus CLL ... ) CLL Symptoms: ... mosquito bites CLL ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... aplasia • ITP ... microglobulin Treatment ... leukemia #CLL ... diagnosis #workup #oncology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... with hypocellular bone ... Treatment: • Consider ... stem cell transplant ... to MDS or acute leukemia
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Increased red cell ... Reticulocytosis/polychromasia ... hyperplasia of bone ... Increased red cell ... #Algorithm #Differential
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... • Bone marrow ... transformation to acute leukemia ... Allogeneic stem cell ... #hematology #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... virus (EBV) • Leukemia ... anemia Treatment ... #Anemia #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... Chronic Myelogenous Leukemia ... Leukemia • Idiopathic ... blood count with differential ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
(CLL) - Summary ... 5) Symptoms of anemia ... Transformation to large cell ... uw_IMresidency #CLL ... #oncology #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Thrombocytopenia - Differential ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Leukemia, Tumour ... ITP • SLE • CLL
Diagram of different types of bone tumors that can occur around the knee on XRay -
different types of bone ... Healed NOF • Giant cell ... ) • Enostosis/bone ... #Differential # ... Radiology #XRay
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