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Polyuria - Differential Diagnosis Algorithm Urine Output > 3L /day Water Diuresis (Urine Osm <100 mOsm/kg) • Primary
kg) • Primary Polydipsia ... Central Diabetes Insipidus ... Nephrogenic Diabetes Insipidus
Classification of Diabetes Insipidus Central or neurogenic diabetes insipidus: - Congenital - Structural malformations affecting the hypothalamus
Classification of Diabetes Insipidus ... neurogenic diabetes insipidus ... Nephrogenic diabetes insipidus ... demeclocycline) Primary polydipsia ... #Diabetes #Insipidus
Causes of Polyuria - Differential Diagnosis Algorithm Polyuria - Urine Output > 3L/day, Increased Urine Volume (>2ml/min) Osmotic
Test • Primary polydipsia ... Central Diabetes Insipidus ... Nephrogenic Diabetes Insipidus
Polyuria - Differential Diagnosis Algorithm Polyuria = >3L Urine output / 24 hours Urine osmolality = 2 (Na
kg • Diabetes Insipidus ... • Primary Polydipsia
Two-step Copeptin algorithm for differential diagnosis of Diabetes Insipidus (DI) Baseline Copeptin < 21.4 pmol/L: • Arginine-stimulated
diagnosis of Diabetes Insipidus ... pmol/L → Primary polydipsia ... DI #Diabetes #Insipidus
Causes of Polyuria - Differential Diagnosis Excess Intake of Water: • Primary polydipsia (a.k.a. "psychogenic polydipsia") •
Water: • Primary polydipsia ... "psychogenic polydipsia ... Diabetes Insipidus
Primary Polydipsia Definition: Excessive volitional water intake Epidemiology: • 6-20% of patients with psychiatric disorders - Most commonly
Primary Polydipsia ... smokers Primary Polydipsia ... Co-morbid diabetes insipidus ... Diagnosis: Diabetes Insipidus ... Alert_Oriented3 #Primary #Polydipsia
Increased Urination - Differential Diagnosis Framework - Increased Volume / Frequency • Increased osmotic load (Increased
resistance (Diabetes insipidus ... osm): Primary Polydipsia
Urine chemistry tests for the diagnostic evaluation of a patient with polyuria UOsm <100 mOsm/Kg (H2O diuresis)
diuresis) • Primary polydipsia ... • Diabetes insipidus
Diabetes Insipidus vs Syndrome of Inappropriate ADH (SIADH) - Comparison Table Diabetes Insipidus - Inadequate ADH SIADH -
Diabetes Insipidus ... Table Diabetes Insipidus ... #Diabetes #Insipidus
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