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diagnosis hematology causes classification acidosis hemolysis lactic typea typeb abg acid acidbase agglutinin base bloodgas cold dehydrogenase disease disorders elevated
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... , spider/snake bites ... udaygulati #Hemolytic ... #Anemia #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... anemia): ... - Drugs (Beta lactam ... Extravascular #Causes #differential ... diagnosis #hematology #anemia
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... anemia, PNH, immune ... disease #LDH #Lactate ... Dehydrogenase #Elevated #differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate ... Urobilinogen #Hemolysis ... #Differential #
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hemorrhage and hemolysis ... result in severe anemia ... anemia Indirect ... elevation Serum lactate ... WBC count and differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... #anemia #hematology
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
Classification and Differential ... delivery: Hypoxemia, Anemia ... Nitroprusside infusion ... Classification #Differential ... #TypeA #TypeB #lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... focus on improving perfusion ... Reduced tissue perfusion ... 30mmHg) - Severe anemia ... Acidosis #Elevation #Differential
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Differentials? ... dosing) L L-lactate ... ) D D-lactate ... Renal failure (uremia ... - Rapid saline infusion
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