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rheumatology systemic causes dermatology erythematosus lupus sle algorithm classification disease generalized management monoclonal nonpalpable oncology palpable paraproteinemias primary pruritus purpura
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... , spider/snake bites ... #Anemia #Differential ... classification #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... Diaqnoses: • ... Pulmonary: pleural effusion ... Prunelle Getten #AdultOnset
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... • Arthropod bites ... renal failure/uremia ... #generalized #dermatology ... Diagnosis #Algorithm
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... 50%): Pleurisy / effusion ... ) Blood (75%): Anemia ... signs #symptoms #diagnosis ... #rheumatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... #Diagnosis #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Lungs: • Pleural effusions ... Seizures • Strokes Skin ... lymphopenia, low PLT • Anemia
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