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diagnosis dermatology erythematosus lupus sle systemic adultonset anemia blanching causes classification clinical disease management monoclonal nonpalpable oncology palpable paraproteinemias purpura
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... , spider/snake bites ... #Anemia #Differential ... classification #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... DIC/TTP/HUS - Hemolytic ... #Diagnosis #hematology ... #rheumatology #
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Sjögrens (15%) Skin ... 50%): Pleurisy / effusion ... normochromic nomocytic or haemolytic ... symptoms #diagnosis #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Arthralgia/arthritis, Skin ... fraction < 20% Differential ... Pulmonary: pleural effusion ... management #treatment #rheumatology
Scleroderma Associated Telangiectasia. If you see them-round, often well circumscribed (but can be matte-like too) &
& blanchable, differential ... Janet Pope @Janetbirdope ... video #blanching #skin ... #dermatology #rheumatology
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 Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... • Coombs (-) hemolytic ... Paraproteinemias #Hematology ... #Monoclonal #Differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Lungs: • Pleural effusions ... Erythematosus #Diagnosis #Rheumatology
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