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clinical ucsdh dermatology skinrash ophthalmology physicalexam diagnosis skin sign nejm fingernails hand rash infection hands peds management pediatrics pharmacology syndrome
Spectrum of activity for systemic antifungal agents Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... micafungin; POS, posaconazole ... .2015.10.012 #Antifungal
Antifungal Agents Frequently Used in Leukemia Antibiogram: • Fluconazole • Itraconazole • Voriconazole • Posaconazole • Caspofungin
Antifungal Agents ... Voriconazole • Posaconazole ... @ZhuoerXie #Antifungal
Antifungal Azoles - Antibiotics Class Overview Mechanism: inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles ... Posaconazole(PO ... Overview #Azoles #Antifungal ... #Voriconazole #Posaconazole
Antifungal Coverage Activity Antibiogram Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Antifungal Coverage ... action of systemic antifungal ... species in which the antifungal ... micafungin; POSA = posaconazole ... PMC3146381/ #Antifungal
Tinea Versicolor (Pityriasis versicolor) NOT a dermatophyte infection Caused by saprophytic, lipid-dependent yeasts Clinical •
Management • Topical antifungals ... • Oral antifungal
Common Medications Known to Prolong QTc Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide Vasopressors/inotropes - Epinephrine, norepinephrine,
promethazine Antifungals ... ketoconazole, posaconazole
Common toxicities of antifungal agents. CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
toxicities of antifungal ... #antifungal #toxicities
Rare Invasive Yeasts - Species and Antifungal Therapy Cryptococcus, Geotrichum, Kodamaea, (Pichia)ohmeri, Malassezia, Pseudozyma, Rhodotorula, Saccharomyces, Saprochaete
- Species and Antifungal ... Invasive #Yeasts #Antifungal
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... Overview #Polyenes #Antifungal
Invasive Candidiasis (IC) Diagnosis: Culture: • Gold standard, but Slow (~2-3 days), 50% sensitivity • Blood Sample •
Tests Conduct antifungal ... Candidiasis #IC #antifungal
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