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Causes of Isolated Neutropenia - Differential Diagnosis Algorithm Congenital Medications • Anticonvulsants • Antibiotics • Antithyroid • Antihypertensive
Neutropenia - Differential ... Septicemia • Gram Positive ... #Neutropenia #Differential ... Algorithm #Causes #Hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Erythrocytosis) - Differential ... Idiopathic JAK-2 Positive ... determination, Smoking, positive ... Erythrocytosis #Differential ... Algorithm #Causes #Hematology
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Aspergillus - Other positives ... infection (IFI) in hematologic ... in HM • False positives ... BAL GM does not differentiate ... CGD pts • False Positives
D-dimer Plasma D-dimer is a product of clot breakdown, released upon degradation of polymerized, crosslinked fibrin. Elevated
i.e. more false positive ... pathophysiology #hematology ... #differential #
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... odds of having positive ... #Bandemia #differential ... neutrophil #WBC #CBC #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
dehydrogenase • Positive ... younger pts) Differential ... hemolytic #anemia #hematology
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm Sequestration: • Splenomegaly Marrow Infiltration: • Hematologic and non-hematologic
Pancytopenia - Differential ... Infiltration: • Hematologic ... and non-hematologic ... #Neutropenia #Differential ... Algorithm #Causes #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunohistochemical studies (to differentiate ... characteristically CD30 positive ... and usually CD15 positive ... classification #hematology
Thrombotic Microangiopathies In Systemic Lupus Erythematosus Dr. Laurent ARNAUD @Lupusreference #TMAs #Thrombotic #Microangiopathies #Systemic #Lupus #Erythematosus #SLE #hematology
Erythematosus #SLE #hematology ... #rheumatology # ... differential #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Non malignant hematologic ... states • Non-hematologic ... Thrombocytosis #Differential ... Algorithm #Causes #Hematology
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