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diagnosis differential rheumatology management erythematosus generalized lupus signs symptoms systemic algorithm behcet causes comparison criteria cryoglobulinemia cryoglobulins disease eularacr grandmal
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... hematological disorders ... to Autoimmune Disorders ... erythematosus (SLE ... diagnosis #types #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ulcers, cutaneous, ocular ... Syndrome: - Ocular ... neuropathy • Absent ... , and SLE) • Urinalysis ... #rheumatology #classification
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Polyneuropathy, ALS), NMJ disorder ... body-), PMR, RA, SLE ... , Vasculitis OVERLAP ... Diagnosis #causes #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... neuropathy • Absent ... affects the skin, neurologic ... cognitive impairment, neurologic ... Cogan syndrome: Ocular
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Erythematous, macular ... ANCA-associated vasculitis ... ) • Endocrine disorders ... • Mesenteric vasculitis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... prognosis • Nodular ... - 5% RS cells absent ... Lymphoproliferative #Disorders ... #Classification
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... ulceration • Ocular ... skin injury) • Neurologic ... Oral aphthae : SLE ... • Arthritis: SLE
Generalized Seizures and Pseudoseizures Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
toxic or metabolic disorder ... grand mal) - Absence ... psychological disorder ... Pseudoseizures #GrandMal #Classification ... #Diagnosis #Neurology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... least 2 joints • Neurologic ... #EULARACR #Classification ... #Criteria #SLE
Photophobia and Headache - Differential Diagnosis Framework Why? • The coexistence of photophobia and headache suggests the potential
without headache • Disorder ... glaucoma - Ocular ... inflammatory disorder ... headache • CNS Vasculitis ... ophthalmology #Neurology
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