12 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
, thiazidic, PPI ... • Immunologic Workup ... • Immunologic Workup ... Lupusreference #druginduced ... #diagnosis #management
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... for alternative causes ... dechallenge • Acute ... #DrugInduced #Liver ... #Algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... range: 18 wks - postpartum ... = nonspecific (nausea ... headache, malaise) → Acute ... rapidly develops (DIC
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Algorithm Vascular Causes ... • Iatrogenic: DILI ... intestines, white blood ... diagnosis #algorithm #hepatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
malignancy (Especially acute ... ABO incompatible blood ... Treat primary cause ... #treatment #management ... #hematology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, thiazidic, PPI ... • Immunologic Workup ... Lupusreference #DrugInduced ... #Lupus #DIL #rheumatology ... diagnosis #treatment #management
Intraoperative Patient Fire - Guidelines for Crises in Anaesthesia
Evidence of fire (smoke, heat, odour, flash, flame)
fire alarm • Dial ... Consider inhalational injury ... depending on degree of injury ... Checklist #Diagnosis #Management ... #Workup
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... pain, dark urine, DIC ... Lung Injury (TRALI ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Transfusion Related Acute ... Lung Injury (TRALI ... Transfusions #diagnosis #management ... #hematology #reactions
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
exclude other causes ... with chest x-ray, blood ... kidney injury with ... HCV, DILI, HCC, ... #Algorithm #hepatology