19 results
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table
Class I agents - Sodium Channel Blockers⠀
Class II
Vaughan Williams Classification ... agents - Sodium Channel ... Class III agents - Potassium ... Channel Blockers ... #Medications #Classification
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
Vaughan Williams Classification ... CLASS 1 - Sodium Channel ... repolarization CLASS 3 - Potassium ... #Pharmacology #Classification ... #Classes #pathophysiology
EKG CHANGES AS A RESULT OF CHANGES IN NA OR K CHANNEL CONDUCTION - GRAPHIC BY
EKG CHANGES AS A ... RESULT OF CHANGES ... IN NA OR K CHANNEL ... JAMES LI, MD #Pathophysiology ... #NaK #Sodium #Potassium
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Phase • Ca++ channels ... Vaughan Williams Classification ... repolarization CLASS 3 - Potassium ... #Pharmacology #Classification ... #Classes #pathophysiology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Decreased ENaC channel ... #Hyperkalemia #Pathophysiology ... Pharmacology #Impaired #Potassium
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #pathophysiology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management Algorithm ... Dialysis Serum potassium ... and ECG changes ... #hyperkalemia #potassium ... diagnosis #management #algorithm
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Heparin) • Sodium-channel ... differential #diagnosis #pathophysiology ... #pharmacology #potassium
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Differential Diagnosis Algorithm ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #high #pathophysiology
Chest Pain / ACS Evaluation Algorithm
Algorithm that attempts to the use history taking (guided by LRs),
ACS Evaluation Algorithm ... Algorithm that ... Diamond-Forrester classification ... Ask about: - Changes ... Evaluation #diagnosis #Algorithm