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Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... Hypophosphatasia Is Low Alkaline ... secondary teeth prematurely ... Symptoms of Low Alkaline ... Diagnosis of Low Alkaline
Liver Function Tests (LFTs)
 - Aspartate aminotransferase (AST) 
 - Alanine aminotransferase (ALT) 
 - Alkaline
aminotransferase (AST) - Alanine ... aminotransferase (ALT) - Alkaline
Algorithm for evaluation of elevated serum alkaline phosphatase.

#Algorithm #elevated #alkaline #phosphatase #AlkPhos #Elevation #Diagnosis #workup
elevated serum alkaline ... Algorithm #elevated #alkaline
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... Bone growth) Alkaline ... stricture/Stones #Alkaline
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
+ ULN ALT) / (alkaline ... phosphatase + ULN alkaline
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Transaminase >> Alkaline ... Cholestatic Pattern - Alkaline
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Interpretation Alanine ... , lungs, RBCs Alkaline
Urine Microscopy Crystals
Uric Acid crystals:
 - Formation promoted by acidic urine
 - Seen in tumor lysis
Formation promoted by alkaline ... Formation promoted by alkaline
Purple Urine Bag Syndrome
Chronic, indwelling catheter + bacteriuria (Providencia, Klebsiella, E.coli*) + alkaline urine
Tryptophan → Indoxyl
Klebsiella, E.coli*) + alkaline
Causes of Respiratory Distress in the Newborn - Differential Diagnosis Algorithm
Premature Newborn
 - Normal CXR:
• Apnea of Prematurity