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diagnosis rheumatology differential dermatology classification mixed nonhcv algorithm cryofibrinogenemia cryoglobulins cutaneous dermatologic dermpath glomerulonephritis gpa granulomatosis lesions manifestations monoclonal nonpalpable
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) IgM
Non-hepatitis C virus Cryoglobulinemia ... MONOCLONAL CRYOGLOBULINEMIA ... /or refractory disease ... #Vasculitis #Management ... Monoclonal #Mixed #Cryoglobulinemic
Non-HCV infectious mixed cryoglobulinemia vasculitis - Diagnosis, causes and management - French Vasculitis Study Group < 5%
infectious mixed cryoglobulinemia ... , causes and management ... < 5% of mixed cryoglobulinemia ... vasculitis Clinical ... #Vasculitis #Rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia ... , in Mixed Cryoglobulinemia ... Triad - Mixed Cryoglobulinemia ... Syndrome: • Clinical ... • Autoimmune diseases
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... hemopathies (4%) • Cryoglobulinemia ... #dermpath #dermatology ... lesions #diagnosis #clinical
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Bone marrow disease ... deficiency • Liver disease ... Von Willebrand disease ... /HSP • Cryoglobulinemia ... Differential #Diagnosis #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Lupus Nephritis, Cryoglobulinemia ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... diagnosis #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... (Granulomatous disease ... Low levels mixed cryoglobulinemia ... differential #diagnosis #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... purpura • Mixed cryoglobulinemia ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... , sepsis or cryoglobulinemia ... cryoglobulins • Negative causes ... Calciphylaxis • Cryoglobulinemia ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
atherosclerotic disease ... most important diseases ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... Differential #Diagnosis #Rheumatology
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