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diagnosis rheumatology dermatology differential classification cutaneous gangrenosum manifestations photo behcet cryofibrinogenemia cryoglobulins dermpath gammopathy gpa granulomatosis lesions monoclonal oncology pathology
Cutaneous Manifestations of Monoclonal Gammopathy • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Extravascular lg Deposits: Systemic ... Cold agglutinin disease ... , Pyoderma gangrenosum ... manifestations #dermatology ... #skin #clinical
Pyoderma Gangrenosum: Autoimmune disorder resulting in a vasculitis which causes slowly progressive ulceration of the skin.
Pyoderma Gangrenosum ... resulting in a vasculitis ... which causes slowly ... a number of systemic ... #Photo #Dermatology
Dermatological semiology of Cutaneous Vasculitis Clinicopathologic correlations • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... Connective tissue disease ... #dermpath #dermatology ... #semiology #signs ... lesions #diagnosis #clinical
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... which may resemble pyoderma ... • Goodpasture syndrome ... Polyangiitis #GPA #dermatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... • Autoimmune diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... ANCA +MPO) • Cryoglobulinemic ... • Cogan Syndrome ... purpura: strong sign ... Low levels mixed cryoglobulinemia
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... (Clinical Dx). ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Episcleritis Signs ... , breast CA - Hematologic ... DDX: - Pyoderma ... #diagnosis #dermatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... • Behcet syndrome ... • Cogan syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... Nephrogenic DI Hematologic ... Vasculitis: • ... 7%, Cryoglobulinemia ... Diagnosis #Management
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