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diagnosis liver causes acute dili rhabdomyolysis aclf cardiology chronic cirrhosis decisionaid dosing druginduced failure hepatitis hepatocellular idiosyncratic induced liverenzymes medications
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... #algorithm #gastroenterology ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Diagnosis Algorithm ... • Ischemia • Autoimmune ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
valproate, azoles), Drugs ... Other: NAFLD, Autoimmune ... Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... /HDS treatments ... steatosis • Autoimmune ... #Diagnosis #Algorithm ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Managing warfarin INR Warfarin dosage must be individualized according to the patient's response to the drug, and
response to the drug ... #management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
- Differential ... , Recreational Drugs ... Other: NAFLD, Autoimmune ... Causes #Acute #algorithm ... #hepatology
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Rhabdomyolysis - Differential ... Diagnosis and Management ... Drugs (Statins), ... Hyperthyroidism), Autoimme ... Treatment: 1
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Framework and Management ... - Toxins - Drugs ... Hyperthyroidism - Autoimmune ... per day until stable
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