18 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Rebound effect from treatment ... Metastatic cancer, Lymphoma ... Kawasaki, Nephrotic syndrome ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... initiation • Differential ... #APML #diagnosis ... #management #hematology ... #oncology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... only curative treatment ... Myelodysplastic #Syndrome ... #Management #treatment ... #hematology #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- Comparison ... • Other hematologic ... #oncology #diagnosis ... #differential # ... hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... disorders (e.g. lymphoma ... #Diagnosis #Management ... #treatment #hematology ... #differential
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... • Tumor lysis syndrome ... and secondary lymphoid ... #Leukemia #Hematology ... #Oncology #Diagnosis
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
diseases LIP: lymphoid ... PSS: Sjogren syndrome ... #Differential # ... Comparison #Table ... #Pulmonary #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
infarction or priapism ... organ damage • Treatment ... Low calcium • Treatment ... #TLS #diagnosis ... #management #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunohistochemical studies (to differentiate ... Treatment • Early ... #diagnosis #classification ... #hematology #oncology ... #management