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diagnosis algorithm causes workup hemolytic palpable pancytopenia platelet purpura thrombocytosis agglutinin blood cold ddxof defects disease extravascular hemolysis inherited intravascular
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Myelogenous Leukemia • Primary ... • Rheumatic disorders ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Pelger-Huet, Macrocytic anemia ... o CML - bcr-able ... #hematology #Markers ... #Differential #
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... Chronic inflammatory disorders ... Post-splenectomy Primary ... Diagnosis #Causes #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /Quantity: • Primary ... - Hemolytic anemia ... #Diagnosis #hematology ... #nonpalpable #dermatology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption Disorders ... Eating disorders ... Acquired Aplastic Anemia ... Primary hematological ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm Consumption Disorders 1. Autoimmune Mediated Pancytopenia 2. Splenic Sequestration Peripheral Destruction
Algorithm Consumption Disorders ... Eating disorders ... Acquired Aplastic Anemia ... Primary hematological ... Diagnosis #Algorithm #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... changes), high MCV anemia ... unclear, or if a primary ... hematologic disorder ... Causes #Workup #hematology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
vasculitis) or disorders ... of primary or secondary ... commonly renal and pulmonary ... #Diagnosis #Dermatology ... Palpable #Algorithm #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
usually IgM) (e.g. primary ... lymphoproliferative disorders ... Extravascular #Causes #differential ... #diagnosis #hematology ... #anemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
15% of AIHA Primary ... • Symptoms of anemia ... • hemolytic anemia ... younger pts) Differential ... #hematology #diagnosis
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