10 results
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook

Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy
Presentation:
- Atypical Clinical ... neuropathies (ataxia, hearing ... and Workup: • ... No additional workup ... sarcoid or other CNS
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... (for secondary APS ... Erythematosus #SLE #CNS
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... Viral Infection Clinical ... Positive Coombs testing ... hemolytic #anemia #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... Clinical Presentation ... Fever is the main clinical ... nervous system (CNS ... #Diagnosis #Management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
) - Symptoms: CNS ... ) - Symptoms: CNS ... (CRS) / ICANS: ... 2–4 days after CRS ... AML (~20 %) and APL
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
on bone marrow leading ... ALL: mediastinal mass ... involvement • 30%: CNS ... : CNS manifestations ... #Oncology #Diagnosis
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Antiphospholipid Syndrome ... (APLS) Testing ... - 1 or more clinical ... #Algorithm #diagnosis ... #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Clinical Features ... CNS • Headache ... Erythematosus #Diagnosis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... Polymyositis or ALS ... Camptocormia (bending ... nucleotidase 1A (Anti cN ... aspiration > 50% of pts
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
plasmacytoma) Clinical ... ribs, vertebrae (thoracic ... the periphery, creating ... • 18F-FDG PET/CT ... #Workup #Hematology