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differential management rheumatology vasculitis algorithm nephrology renal syndromes treatment acidosis actinomyces actinomycosis aniongap antigbm basement classification clinical ct disseminated giomeruiar
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... - Differential Diagnosis ... hemorrhage + rapidly progressive ... Vasculitis - Anti-GBM ... Positive (ANCA + anti-GBM
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... pathophysiologic causes ... With associated pulmonary ... Disease (Goodpasture's ... RPGN #Rapidly #Progressive
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm No Objective Weakness • Cardio-pulmonary disease
Causes of Peripheral ... Weakness • Cardio-pulmonary ... disease • Anemia ... Lead toxicity • Progressive ... Peripheral #Weakness #Neurology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... life-threatening diseases ... Inflammatory eye disease ... Goodpasture's cause ... Path: rapidly progressive
Rhombencephalitis BACTERIAL - Listeria (biphasic illness with bulbar dysfunction occurring later) - Mycobacterium tuberculosis - Pneumococcus - Brucella - Borrelia (Lyme Disease) -
Borrelia (Lyme Disease ... ; Positive for anti-ganglioside ... encephalomyelitis - Progressive ... #Differential #Diagnosis ... #Causes #Neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
proteinuria, Rapidly progressing ... affects the skin, neurologic ... is 50 years • Progressive ... immune GN (rapidly progressive ... tract, and often causes
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis Causes of High-anion Gap Acidosis: • Lactic acidosis
Chronic progressive ... kidney disease ... Nonsteroidal anti-inflammatory ... #differential #diagnosis ... #causes #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... resulting in rapidly progressive ... hemorrhage Diagnosis ... Goodpastures #AntiGBM #diagnosis ... #nephrology #pulmonary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... proteinuria, rapidly progressing ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... Urticarial Vasculitis (anti-C1q
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Prevalence: 1-2 cases ... Syndrome: • Progressive ... poisoning, Parkinson's disease ... Baclofen • Severe Disease ... Management #treatment #neurology
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