22 results
Erythropoiesis (RBC Production and Maturation)

Pluripotent hematopoietic stem cell → Proerythroblast (a.k.a. pronormoblast) → Erythroblast (a.k.a. normoblast)
Erythropoiesis ( ... Proerythroblast (a.k.a. pronormoblast ... EricsMedicalLectures/ #Erythropoiesis
Pity this Giant Pronormoblast from an elderly pt w pure red cell aplasia. In the proper
Pity this Giant Pronormoblast ... dannyjlubinpath #Giant #Pronormoblast
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
hemolysis, exogenous erythropoietin ... conditions that impair erythropoiesis
#Erythropoietin
#Erythropoietin
Exogenous Testosterone Side Effects
 • Mood disorder, Depression, Aggression
 • ↑ Erythropoiesis
 • Hypogonadism +/-BPH, prostate
Aggression • ↑ Erythropoiesis
Medications for the Management of Anemia

TREATMENT OF ANEMIA
 - Cyanocobalamin/B12
 - Erythropoietin/epoetin alfa
 - Darbepoetin alfa
Cyanocobalamin/B12 - Erythropoietin
Conversion - Epoetin alfa (Procrit®) to Darbepoetin alfa (Aranesp™)

#Epoetin #Darbepoetin #Erythropoietin #Conversion #Table #ESAs #Procrit #Aranesp
#Darbepoetin #Erythropoietin
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
simulation • Erythropoiesis
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
• Ineffective Erythropoiesis
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
Positive - Low/Normal Erythropoietin ... Polycythemia Vera Erythropoietin