1213 results
Renal Effect of NSAIDs Inhibition of Prostaglandin Synthesis

 - Renal disease, Cardiovascular disease -> Decreased renal
Inhibition of Prostaglandin ... NSAlDs inhibit prostaglandin ... #NSAIDs #Prostaglandins ... #Pharmacology #Pathophysiology
Arachidonic acid pathway and drugs which affect it.

#Pharmacology #Pathophysiology #ArachidonicAcid #Pathways #COX #Prostaglandins #Prostacyclins #Leukotrienes #Synthesis

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#Pharmacology #Pathophysiology ... Pathways #COX #Prostaglandins
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
Effects of Prostaglandins ... Kidney Effects of Prostaglandins ... role of these prostaglandins ... production of renal prostaglandins ... • Prostaglandins
Rigors And Bacteremia - Overview

• Rigors are a response to the release of cytokines and prostaglandins
cytokines and prostaglandins ... PATHOPHYSIOLOGY: ... induces synthesis of Prostaglandins ... Rigors #Bacteremia #Pathophysiology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... Change Disease via Prostaglandin ... nephrology #Effects #pathophysiology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... DOAC #Bridging #Dosing ... Rivaroxaban #Edoxaban #Loading
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
point" raised by prostaglandin ... Antipyretics block prostaglandin ... antipyretics to block prostaglandin ... peripherally - Cooling
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
mediators (e.g. prostaglandins ... #Anaphylaxis #pathophysiology
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... gastropathy • Dosing ... #indications #dosing
Fever - Pyrogen Pathophysiology

EXOGENOUS PYROGEN
 • Bacteria: Lipopolysaccharide components, peptidoglycans and muramyl peptide derivatives, Toxins
 •
Fever - Pyrogen Pathophysiology ... Induce synthesis of Prostaglandins ... Fever #Fever #Pathophysiology