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SPICE (SPACE) Organisms
 - Colloquial acronym for gram-negative bacteria that have inducible, chromosomal beta-lactamase genes known
genes known as AmpC ... Indole-positive" Proteus ... Bacteria #Organisms #AmpC
SPICE (SPACE) Organisms

Gram-negative bacteria that have inducible, chromosomal beta-lactamase genes known as AmpC - Resistance may
genes known as AmpC ... Indole-positive" Proteus ... Bacteria #Organisms #AmpC
Causes Abnormal Urine Color - Differential Diagnosis
Turbid White Urine (Albinuria):
 • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal Urine ... * Green Urine: ... : • Purple Urine ... UTI caused by (Proteus ... , Tyrosinuria, Proteus
Metabolic Pathways of Purple Urine Bag Syndrome: Adopted from chart originally published in Purple Urine Bag
Pathways of Purple Urine ... published in Purple Urine ... commonly grown in the urine ... Escherichia coli, Proteus ... #PUBS #Purple #Urine
Coverage of common antibiotics used in the hospital

For empiric coverage, first define the type of infection,
AmpC. ... Dapto, Linezolid Amp-S
What the Color of Urine Can Tell You - Differential Diagnosis by Urine Color
Clear: excess water
Pale
What the Color of Urine ... Differential Diagnosis by Urine ... Purple (Purple Urine ... Proteus) - BWH ... BrighamChiefs #Urine
Antibiogram with shading indicating organisms associated with inducible AmpC beta-lactamase. 

#Antibiogram #AmpC #Resistance #SPICE #Organisms #Pathogens
with inducible AmpC ... #Antibiogram #AmpC
Urine Microscopy Crystals
Uric Acid crystals:
 - Formation promoted by acidic urine
 - Seen in tumor lysis
Urine Microscopy ... promoted by acidic urine ... promoted by alkaline urine ... Proteus, Klebsiella ... independent of urine
Protease Inhibitors 

Protease Inhibitors are a class of commonly used antiretroviral medications for management of HIV.
Protease Inhibitors ... Protease Inhibitors ... inhibit the enzyme protease ... /ambcarerx #Protease
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
2-2.5% or 24h Urine ... 2-2.5% or 24h Urine ... • Cisplatin, Amp