12 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... #management #hematology ... #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
malignancies Treatment ... Interleukin-2) • Tumor ... Methotrexate • AIN ... #AKI #Cancer #Oncology ... #Differential #
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... (both ALL and AML ... Walid Malki, MD, MS ... #TLS #oncology ... #management #UricAcid
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
develop leukostasis syndrome ... smear: Blasts APML ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... #Oncology #Diagnosis
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
pustulosis, pustular psoriasis ... , psoriasis vulgaris ... and lower jaw Treatment ... Rheumatology #diagnosis #management ... #Dermatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... abdomen if abdominal pain ... antibiotics TLS (tumor-lysis ... : - Seen with AML ... (~20 %) and APL
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
with: - Thymic tumors ... thyroid, Sjogren syndrome ... life-threatening Differential ... immunologic assay - MuSK ... Gravis #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... blood count with differential ... marrow studies Treatment ... #diagnosis #hematology ... #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behcet disease) Differential ... Arthritis, AS Treatment ... interferon alfa, or tumor ... Nonsurgical abdominal pain ... #diagnosis #management
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... : • Tumor-like ... Sensitivity to pain ... sclerosis #diagnosis #management ... #neurology #treatment