37 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Skin Conditions ... Plaques • Psoriasis ... arthritis • Psoriatic ... #joint #pain #skin ... differential #diagnosis #rheumatology
Joint Disorders - Differential Diagnosis Algorithm
Monoarthritis
 • Septic
 • Crystalline
     - Gout
Molecular Mimicry” • Psoriatic ... arthritis - with the skin ... disorder psoriasis ... should have other symptoms
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – symptoms ... Symptoms: Tiredness ... , Dry coarse skin ... Goitre), Dry skin ... #PhysicalExam #Endocrinology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
LcSSc) - distal skin ... thickening Signs and Symptoms ... changes): skin ... Scleroderma #SSc #rheumatology ... diagnosis #signs #symptoms
Cushing Syndrome - Signs and Symptoms
Generalized: Weight gain, Slow healing of cuts, Increased risk of infections,
Syndrome - Signs and Symptoms ... Muscular: Weakness Skin ... Syndrome #Signs #Symptoms ... #diagnosis #endocrinology
Psoriatic Arthritis: Pathogenesis and Clinical findings

In tendons and connective tissues:
 • Enthesitis  - Pain/tenderness over
Psoriatic Arthritis ... are inflamed In skin ... : • Psoriatic ... plaques on skin, ... diagnosis #signs #symptoms
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
Hyperthyroidism - Symptoms ... Menorrhagia - Skin ... • Skin is ... #Hyperthyroid #Symptoms ... Signs #Diagnosis #endocrinology
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
trigger - Direct skin ... and duration of symptoms ... 50% of patients Skin ... angioedema Other symptoms ... Urticaria #diagnosis #rheumatology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
bone, joint, and skin ... • Pustular skin ... pustulosis, pustular psoriasis ... , psoriasis vulgaris ... SAPHO #Syndrome #Rheumatology