63 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... function test, ANA (e.g ... ), (neurologic/psychiatric ... or if a primary hematologic ... #Workup #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... Differential #diagnosis #hematology
Pericarditis can be seen on EKG with diffuse ST elevations without reciprocal changes along with diffuse
can be seen on EKG ... First line treatment ... in refractory cases ... Cardiology #Diagnosis #Signs
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
quadrant discomfort Signs ... autoimmune disease (e.g ... Diagnose PBC if 2/3 criteria ... specific ANAs (e.g ... Diagnosis #Algorithm #hepatology
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
cardiac syncope, e.g ... frequently benign causes ... life-threatening causes ... orthostatic vital sign ... The treatment strategy
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: ARDS Berlin Criteria ... without other cause ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Summary Diagnostic Criteria ... present, symptoms, signs ... Splenomegaly Treatment ... • Treatment is ... #hematology
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
) - Diagnostic Criteria ... response to 1 g/kg ... - No other cause ... - No other cause ... HRSAKI #HRSNAKI #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... organ damage • Treatment ... unless worrisome EKG ... diagnosis #management #hematology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Lhermitte’s sign ... Signs and symptoms ... McDonald diagnostic criteria ... Multiple Sclerosis Treatment ... management #neurology #treatment