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diagnosis hepatology management differential algorithm primary signs treatment pathophysiology syndrome pbc cholangitis classification clinical dermatology hematology lfts liver photo rash
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... Algorithm Symptoms ... of autoimmune disease ... Diagnose PBC if 2/3 criteria
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... cholestasis → Cirrhosis ... PBC Signs and Symptoms ... #Cirrhosis #PBC
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
other autoimmune diseases ... processes like primary biliary ... cirrhosis (PBC) ... with systemic diseases ... (SLE) Signs / Symptoms
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
) - Diagnostic Criteria ... No haematuria, Normal ... cause of kidney disease ... - Cirrhosis ... cause of kidney disease
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Cholestatic disease ... US — Normal Bile ... Infiltrative • Cirrhosis ... Duct Stone • Biliary
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
to multi-focal biliary ... • CIRRHOSIS - ... Progression to cirrhosis ... colorectal and hepato-biliary ... Care focuses on symptom
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Extrahepatic - Biliary ... Choledocholithiasis, Biliary ... - Obstruction: Biliary ... function may be abnormal ... hepatitis: < 1 • Cirrhosis
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... metabolic syndrome criteria ... include extrahepatic biliary ... alcohol-related liver disease ... non-alcoholic fatty liver disease
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
ANA ≠ Autoimmune Disease ... context of other symptoms ... • Rheumatic Diseases ... Hepatitis, Primary Biliary ... Cirrhosis, Drug-Induced
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... /or prognostic criteria ... 1.5x ULN and/or abnormal ... Manage symptoms ... Stage & survey disease
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