28 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Triggers: ATRA treatment ... Diagnosis: >3 symptoms ... Renal Failure Treatment ... #oncology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Summary Diagnostic Criteria ... When present, symptoms ... • "Vasomotor" symptoms ... transformation into AML ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... rapid onset of symptoms ... smear: Blasts APML ... #Leukemia #Hematology ... #Oncology #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: ARDS Berlin Criteria ... ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
• Rome IV Criteria ... last 3 months + symptom ... for diagnosis Treatment ... Gastroenterology and Hepatology ... gastroenterology #treatment
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Splenomegaly 5) Symptoms ... transformation) Treatment ... Constitutional symptoms ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management
Diagnosis - Caine Criteria (2 of
Diagnosis - Caine Criteria ... Anorexia nervosa Treatment ... Encephalopathy • A prompt treatment ... can improve symptoms ... Diagnosis #Management #neurology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... → no immediate treatment ... : - Seen with AML ... (~20 %) and APL ... #Emergencies #Oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
pathogens, including PML ... Antimicrobial treatment ... status, and focal neurologic ... confusion, and focal neurologic ... InfectiousDiseases #Neurology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... microglobulin Treatment ... Transform to DLBCL, PML ... diagnosis #workup #oncology ... #hematology