18 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
DAAs #Antivirals #table ... #treatment #hcv ... infectiousdisease #hepatology ... HepatitisC #Management #Pharmacology
Anti-infective stewardship, including tips for using anti-infectives wisely, criteria for stepdown from IV to PO dosage
anti-infectives wisely, criteria ... #pharmacology #antibiotics ... #medications #table ... #treatment #drugs
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Summary Diagnostic Criteria ... When present, symptoms ... • "Vasomotor" symptoms ... the reduction of symptoms ... #hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
• Rome IV Criteria ... last 3 months + symptom ... for diagnosis Treatment ... Gastroenterology and Hepatology ... gastroenterology #treatment
Summary of meta-analysis of pharmacotherapy trials in BPD
https://www.cochrane.org/CD005652/BEHAV_psychological-therapies-borderline-personality-disorder
Meta-analyses of RCTs were undertaken for the following outcomes:
outcomes: BPD symptoms ... with ‘treatment ... summarised in Tables ... EBM #Management #Pharmacology ... Effectiveness #Table
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
arterioles -> less able ... Extrapyramidal Symptoms ... #SideEffects #pharmacology ... #diagnosis #psychiatry
Long-Acting Injectable (LAI) - Atypical Antipsychotics 
INVEGA TRINZA 3 MONTHS 
ARISTADA 2 MONTHS 
INVEGA 1 MONTH
SUSTENNA
are used in the treatment ... Pharmacists are able ... Antipsychotics #Pharmacology ... #Duration #Psychiatry
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology