10 results
Lupus Nephritis Primer
Class I - Minimal Mesangial
Class II - Mesangial Proliferative
Class Ill - Focal Proliferative
Class IV
VI - Advanced Sclerosing ... Lupus #Nephritis #SLE ... differential #diagnosis #management ... #nephrology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Lhermitte’s sign ... Signs and symptoms ... objective evidence of neurologic ... #diagnosis #management ... #neurology #treatment
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... in 10 to 40% of SLE ... VI - Advanced sclerosing ... #rheumatology # ... nephrology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Erythematosus #SLE ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Amyotrophic Lateral Sclerosis ... finding of lateral sclerosis ... of UMN and LMN signs ... #neurology #diagnosis ... #management
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
• Symptoms and signs ... : - Multiple sclerosis ... Behcet disease - SLE ... Scleroderma, Systemic sclerosis ... disorders #diagnosis #neurology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
rheumatoid arthritis, SLE ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management ... #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Oral aphthae : SLE ... Syndrome #diagnosis #management ... #signs #symptoms ... #rheumatology #
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
• Bilateral signs ... Evaluate for NMO, SLE ... Disorders: - SLE ... Myelitis #diagnosis #management ... #neurology #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
diseases, such as SLE ... , particularly scleritis ... purpura: Strong sign ... tenderness - decreased pulsation ... Differential #Diagnosis #Rheumatology