27 results
Aortic Dissection Pearls
Aortic dissection is caused by a tear in the tunica intima, the innermost layer
is caused by a ... Examine for: • Pulse ... deficit/differential ... #Dissection #diagnosis ... #management #vascular
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Bone/Joint Causes ... Limb ischemia • Aortic ... refill - Poor pulses ... differential #diagnosis
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Causes of Bone/Joint ... • Differentiate ... #Disease #differential ... #diagnosis #causes ... #hematology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... Like in this case ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup #differential
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential ... Diagnosis Framework ... HEMATOLOGIC ... #differential # ... diagnosis #cancer
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... effusions, weight gain ... initiation • Differential ... #diagnosis #management ... #hematology #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... : Blast crises ... , fever, joint pain ... #Leukemia #Hematology ... #Oncology #Diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #pain #differential ... #diagnosis #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... Diagnosis: ... Rule out other causes ... #diagnosis #management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... and fingers, or pain ... the face (many differential ... search ANA and aPL