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diagnosis rheumatology cardiology endocarditis erythematosus systemic classification conditions dermatology embolism extrarticular infectiousdiseases joint management nonpalpable pain palpable pathophysiology purpura signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Features of Systemic Lupus ... (SLE) General: ... Butterfly rash, Vasculitis ... Endocarditis, Aortic ... ) Blood (75%): Anemia
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Thrombosis - Differential ... atherosclerotic lesions ... 19 - PNH - Vasculitis ... pathophysiology #hematology ... #differential #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... hemorrhagic skin lesions ... - Hemolytic anemia ... Associated - SLE ... #Diagnosis #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemic skin lesions ... Thrombosis and arterial ... such as systemic lupus ... diminished, or tender pulses ... , and SLE) • Urinalysis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... papulosquamous lesions ... permanent alopecia Differential ... ANCA-associated vasculitis ... lymphopenia, low PLT • Anemia
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... diseases, such as SLE ... < 30 years • Aorta ... claudication, pulse ... Arteritis): • Aorta
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Lyme disease, Vasculitis ... Rheumatic fever • Aortic ... Diminished peripheral pulses ... #joint #pain #differential ... #diagnosis #rheumatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
CA • Involves aortic ... • Autoimmune (SLE ... Marantic (NTBE) Differential ... valvular disease • Vasculitis ... Leukocytosis, anemia
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
- Overview and Differential ... Ovarian CA, involves aortic ... • Autoimmune (SLE ... valvular disease • Vasculitis ... Leukocytosis, anemia
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