17 results
Giant Cell (Temporal) Arteritis: Pathogenesis and investigations
Risk Factors:
 - Unclear environmental triggers (may be viral, not
Cell (Temporal) Arteritis ... yrs old; F>M Signs ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... < 30 years - Aorta ... Presentation - Systemic Symptoms ... purpura: strong sign ... diminished, or tender pulses
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
of giant cell arteritis ... posterior ciliary arteries ... Doppler US : halo sign ... #Rheumatology #Ophthalmology ... #Diagnosis #Algorithm
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... diminished, or tender pulses ... < 30 years • Aorta ... claudication, pulse ... ): • Aorta and
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
, small-vessel vasculitis ... meningitis), MCC CNS symptoms ... inhibitors • Uveitis- Ophthalmology ... #management #signs ... #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Butterfly rash, Vasculitis ... of hip (rare), Arthritis ... Endocarditis, Aortic ... erythematosus #signs ... #symptoms #diagnosis
Takayasu’s Arteritis: Pathogenesis and clinical findings

 - Fatigue, weight loss, low grade fever, arthralgias
 - Incr
Takayasu’s Arteritis ... , CRP, WBC - Aortic ... Decr palpable pulses ... #Vasculitis #Diagnosis ... #Signs #Symptoms
Giant Cell Arteritis (Polymyalgia Rheumatica and Cranial Arteritis): Pathogenesis and Clinical Findings
 - Morning Stiffness (>1
Giant Cell Arteritis ... Rheumatica and Cranial Arteritis ... CranialArteritis #Pathophysiology ... #Signs #Symptoms ... #Diagnosis #Vasculitis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... systemic sx + signs ... = vasculitis vs ... required +/- prompt ophthalmology ... #Symptoms #Diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Arthralgia's (common), arthritis ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs ... #Symptoms