12 results
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Petechial/Purpuric ... ) purpura occurs ... Nonpalpable purpura ... with petechiae/purpura ... #Purpuric #Rash
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... - Differential ... BrighamChiefs #Purpura ... #nonpalpable #palpable ... #Causes #Differential
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... - Differential ... C), Pigmented purpuric ... BrighamChiefs #Purpura ... #nonpalpable #palpable
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... Acute Infectious Purpura ... PURPURA: Vasculitis ... #nonpalpable #dermatology
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Purpura Purpura ... with lower leg purpura ... Palpable purpura ... Tip: To differentiate ... #Legs #Rash #clinical
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... purpura (16%) ... purpura • Vesicles ... overlying purpuric ... Henoch-Schönlein purpura
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
areas of the body Purpura ... Purpura due to vasculitis ... is usually palpable ... Wet purpura is the ... #Petechiae #Purpura
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis: • Purpura ... Henoch Schonlein Purpura ... erythematous nodules, purpura ... purpura: strong ... purpura.
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Arthralgia - Purpura ... Syndrome: • Clinical ... triad of Palpable ... purpura, Arthralgia ... Henoch-Schönlein purpura
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
organ damage Clinical ... Petechiae • Purpura ... • Palpable variants ... Hemorrhagic bullae • Purpura ... causes #treatment #management