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Algorithm for Diagnosis of the Petechial / Purpuric Rash

Febrile/Toxic, Palpable: 
 - Meningococcaemia, Disseminated Gonococcal Infection,
/ Purpuric Rash ... Endocarditis, Henoch-SchönIein ... Purpura Febrile ... Purpura By ... #Purpuric #Petechiae
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH 

These rashes can be especially challenging and are
associated with devastating differential
Petechial/Purpuric ... endocarditis, RMSF, and Henoch-Schönlein ... purpura. ... purpura. ... #Petechiae #Purpural
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... hemostasis: - Thrombocytopenia ... infection - RMSF - Henoch ... Schonlein Purpura ... Rash: - Purpura
Causes of Purpura - Differential Diagnosis
Disruption in Vascular Integrity: 
 • Trauma, Infection, Vasculitis, Drug induced
Causes of Purpura ... C), Pigmented purpuric ... BrighamChiefs #Purpura ... #nonpalpable #palpable ... #Causes #Differential
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Purpura Purpura ... Palpable purpura ... Tip: To differentiate ... Thrombocytopenia ... #dermatology #HSP
Causes of Purpura - Differential Diagnosis
Non-PalpabIe → Palpable
 • Thrombocytopenia (HIT, ITP/HUS), Coagulation defects (DIC, warfarin
Causes of Purpura ... - Differential ... Thrombocytopenia ... BrighamChiefs #Purpura ... #Causes #Differential
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... Acute Infectious Purpura ... OF PALPABLE PURPURA ... Ig A vasculitis/HSP
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... , Palpable purpura ... • Palpable purpura ... Vesicles overlying purpuric ... purpura • Mixed
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... purpura ... Henoch—Schönlein ... purpura, SLE ... - Scurvy #Purpura
Bleeding manifestations 
Petechiae are small, flat, red, discrete areas of skin bleeding that are typically <2
areas of the body Purpura ... Purpura due to vasculitis ... is usually palpable ... Wet purpura is the ... #Purpura #Bruise