13 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... PURPURA: Platelet ... Diagnosis #hematology ... #rheumatology # ... #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
purpura (16%) ... purpura • Vesicles ... overlying purpuric ... reticularis Differential ... Henoch-Schönlein purpura
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
Palpable Purpura ... Henoch Schonlein Purpura ... on tuberculosis treatment ... #Purpura #Henoch ... #dermatology #skin
Henoch Schonlein Leg Rash - Palpable Purpura
Purpura: Low Platelets or Vasculitis?
45 years old, seen in our
Purpura Purpura ... Palpable purpura ... Tip: To differentiate ... Rash #clinical #photo ... #dermatology #HSP
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Thrombocytopenic Purpura ... Thrombocytopenic #Purpura ... #management #treatment ... #rheumatology # ... hematology
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Crohn's disease Palpable ... purpura • Hypersensitivity ... Henoch Schönlein purpura ... Sarcoidosis #dermatology ... #diagnosis #rheumatology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment ... thrombocytopenic #purpura ... Diagnosis #Table #Hematology
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Involving the Skin - Differential ... Vessel: Petechiae, Palpable ... purpura, Hemorrhagic ... Vasculitis #skin #dermatology ... #rheumatology #
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Petechiae • Purpura ... • Palpable variants ... Hemorrhagic bullae • Purpura ... + Bleeding Treatment ... #management #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... (Petechial or purpuric ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology