8 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... Proteinuria often ... Nephrotic yndrome—podocyte ... diabetes)) #Glomerular ... #Classification
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
Nephritic vs Nephrotic ... hematuria and/or proteinuria ... the patient have glomerular ... #Nephritic #Nephrotic ... Syndrome #Comparison #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria, proteinuria ... immune deposits in glomeruli ... nephropathy, lupus nephritis ... post-infectious GN Anti-Glomerular
This image shows scanning EM of a proteinuric glomerulus with capillary loop showing widening and partial
of a proteinuric ... glomerulus with ... interdigitating podocyte ... arkanalabs #glomerulus ... ElectronMicroscopy #SEM
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Differential Diagnosis Algorithm ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular ... range) proteinuria
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... presenting with overt glomerular ... Cytomegalovirus; GBM = glomerular ... #diagnosis #glomerular ... #proteinuria #nephrotic
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
SLE Hallmark = proteinuria ... therapy Goal: proteinuria ... by 12 months Classification ... Focal LN (<50% of glomeruli ... Diffuse LN (>50% of glomeruli
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
RBC casts, +/- proteinuria ... formation along glomerular ... immune deposits on EM ... glomerulopathy, radiation nephritis