23 results
Several artifacts can cause significant and potentially misleading alterations to measured RBC parameters: 
1. Old samples
#Drepanocytes #Schistocytes ... #Pyknocytes #Elliptocytes
Schistocytes - The arrows point to schistocytes which are fragmented red blood cells. Also called schizocytes,
Schistocytes - The ... arrows point to schistocytes ... Also called schizocytes ... Schistocytes are ... Schistocytes are
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis of schistocytes ... BCM_InternalMed #schistocytes
Schistocytes can assume a shape resembling natural or man-made objects such as arrowheads, fish, collar buttons,
Schistocytes can ... #HelmetCells #Schistocytes
Causes of AKI in Pregnancy - Differential Diagnosis
Creatinine - Platelets - Transaminases - LDH - PT/PTT
LDH - PT/PTT - Schistocytes
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Megaloblastic Anemia Schistocytes
Pathologic Red Blood Cell (RBC) Morphologies and Associated Diseases

Acanthocyte (spur cell),  
Basophilic stippling, 
Bite cell,
sideroblast, Schistocyte
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
likely: • Smear: schistocytes
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
transfusions) • Schistocytes
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
blue arrow) - schistocytes