288 results
Common Medications Known to Prolong QTc
Antiarrhythmics - Amiodarone, sotalol, flecainide, quinidine, dronedarone, dofetilide
Vasopressors/inotropes - Epinephrine, norepinephrine,
Known to Prolong QTc ... sotalol, flecainide, quinidine ... Chloroquine, mefloquine, quinine ... pseudoephedrine #QTc
QT/QTc- Interval
•	Start of Q-wave to end of the T-wave (time of ventricular depolarization + repolarization).
•	Life threatening
/QTc interval may ... drug effects (quinidine ... calculating the QTc ... Bazett formula, QTc ... • Hodges [QTc =
Drug-Induced Prolonged QTc

QTc >500ms is an independent risk factor for developing Torsades des Pointes (TdP)
Drugs causing
Drug-Induced Prolonged QTc ... QTc >500ms is ... Drugs causing QTc ... Procainamide, Quinidine ... Induced #Prolonged #QTc
Torsades de Pointes 
•Precipitated by drugs that prolong the QT interval 
•Class IA antidysrhythmics (procainamide, quinidine)
that prolong the QT ... (procainamide, quinidine
The JT Interval and Pro-Arrhythmic Risk
Measured from the J-point to the end of the T-wave, the
JTc=QTc-QRS When ... than prolonged QT ... Interval #JTInterval #QTc
Drugs Implicated in Hemolytic Anemia
 • Hapten (Drug binding to RBC membrane): Penicillin, Cephalosporin, Tetracycline, Tolbutamide,
, Probenciden, Quinidine ... , Quinine, Probenecid
Quinidine produces the following ECG changes:
1. Prolongation of Q-T interval:
2. Prolongation of QRS complex:
3. Prominent V
Quinidine produces ... Cardiology #ECG #EKG #Quinidine
Common toxicities of antifungal agents. 
CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
= intravenous; QTc ... = corrected QT
Want to remember what drugs prolong the QT interval? Remember COLLAPSE - Kitty Canavan @KathrynCanavan1
#Diagnosis #Peds
drugs prolong the QT ... COLLAPSE #Mnemonic #QTc
Antiarrhythmic Drugs

CLASS IA
 • Procainamide, Quinidine, Disopyramide
CLASS 1B
 • Lidocaine, Mexiletine
CLASS 2
 • Propranolol, Esmolol
CLASS 4
Procainamide, Quinidine